Many cats are uncooperative with oral dosing; especially when they have GI issues, an aversion to the taste of the active medication, or when they require long-term, daily administration of drugs such as methimazole. Owners may also have challenges administering oral medications on a consistent basis. When oral formulations are not a good option, transdermal vehicles provide an alternative route of administration for a limited number of medications.
The efficacy of a transdermal preparation depends upon both the quality of the base selected and its specificity to the API (active pharmaceutical ingredient) prescribed. Best Pet Rx custom compounds transdermal preparations with Lipoderm® gels; a line of proprietary and validated transdermal bases developed by PCCA. Lipoderm® is smooth and creamy. It absorbs into the skin quickly and resists build up on the skin surface. It is physically stable and does not separate under refrigeration.
Transdermal medications require precise doses. Pen delivery systems, though popular, may have issues with dose calibration. To ensure proper dosing, we dispense in clearly graduated, easy to use 1 ml syringes.
The maximum strength concentration for transdermal preparations is generally 300 mg/ml. A dose of 0.1 ml is easiest for pet owners to apply.
We custom compound patient-specific orders using standardized formulas and the guidance of veterinary pharmacology experts who select the appropriate Lipoderm® base to match each API. Lipoderm® can be formulated with a wide range of API’s including those with high molecular weights allowing us to offer new transdermal medication options.